Comparison of HCV RNA assays for the detection and quantification of hepatitis C virus RNA levels in serum of patients with chronic hepatitis C treated with interferon

Author(s):  
M.-A. Trabaud ◽  
F. Bailly ◽  
S. N. Si-Ahmed ◽  
P. Chevallier ◽  
M. Sepetjan ◽  
...  
Hepatology ◽  
1994 ◽  
Vol 20 (5) ◽  
pp. 1115-1120 ◽  
Author(s):  
Masahide Oshita ◽  
Norio Hayashi ◽  
Akinori Kasahara ◽  
Hideki Hagiwara ◽  
Eiji Mita ◽  
...  

The Lancet ◽  
1993 ◽  
Vol 341 (8859) ◽  
pp. 1501-1504 ◽  
Author(s):  
J.Y.N Lau ◽  
G.L Davis ◽  
J Kniffen ◽  
K.-P Qian ◽  
M.S Urdea ◽  
...  

1994 ◽  
Vol 26 (3) ◽  
pp. 263-270 ◽  
Author(s):  
Zhi Bing Yun ◽  
Olle Reichard ◽  
Margaret Chen ◽  
Joakim Lundeberg ◽  
Gunnar Norkrans ◽  
...  

1994 ◽  
Vol 107 (1) ◽  
pp. 196-199 ◽  
Author(s):  
Tse-Ling Fong ◽  
Boontar Valinluck ◽  
Sugantha Govindarajan ◽  
Francine Charboneau ◽  
Rodney H. Adkins ◽  
...  

2016 ◽  
Vol 10 (2) ◽  
pp. 417-422 ◽  
Author(s):  
Akira Sato ◽  
Toshiya Ishii ◽  
Kayo Adachi ◽  
Hideaki Takahashi ◽  
Fumiaki Sano ◽  
...  

Following interferon-based therapy for chronic hepatitis C, the negativity of hepatitis C virus RNA is essential to achieve viral clearance at the end of treatment. We report a case of clearance of chronic hepatitis C virus infection following early discontinuation (at 6 weeks) of peginterferon plus ribavirin therapy, without negativity for hepatitis C virus RNA during the treatment period. The patient was a 76-year-old Japanese male infected with hepatitis C virus genotype 1b and TT of IL28B rs8099917. Hepatitis C virus RNA remained positive at persistently low levels for more than 2 months after the cessation of therapy and became negative at 7 months after the discontinuation of therapy. Spontaneous clearance of hepatitis C virus RNA can occur following antiviral failure in patients with persistently low viral loads, and virological follow-up is therefore necessary in chronic hepatitis C virus infection, even after antiviral failure.


Sign in / Sign up

Export Citation Format

Share Document